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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9533 | BC-LI-0186 | 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide | Others |
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei... | |||
T4045 | Epetraborole hydrochloride | GSK2251052 hydrochloride | Antibacterial |
Epetraborole hydrochloride (GSK2251052 hydrochloride) is a potent and selective leucyl-tRNA synthetase inhibitor. | |||
TL0005 | 3,5-O-Dicaffeoylquinic acid | Isochlorogenic Acid A,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid | Others |
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. ... | |||
T71168 | Epetraborole R-Mandelate | ||
Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor. | |||
T71458 | Epetraborole | ||
Epetraborole is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. | |||
T11497 | Ganfeborole HCl | GSK3036656 HCl,GSK656 HCl | Antibacterial |
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM). | |||
T60405 | GSK-3036656 free base | GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656 | |
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1]. | |||
T11840 | Leu-AMS | Others | |
Leu-AMS, a leucine analogue and potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, exhibits cytotoxic effects in both cancer and normal cells and hampers bacterial growth. It specifically inhibits... | |||
T11841 | Leu-AMS R enantiomer | Others | |
Leu-AMS R enantiomer is the R enatiomer of Leu-AMS. Leu-AMS is a potent leucyl-tRNA synthetase (LRS) inhibitor that inhibits the bacteria growth. | |||
T39296 | DS86760016 | ||
DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and ... | |||
T38773 | LeuRS-IN-1 hydrochloride | ||
LeuRS-IN-1 hydrochloride is a potent and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS). It has IC 50 and Kd values of 0.06 μM and 0.075 μM, respectively, for M.tb LeuRS. Additionally, Leu... | |||
T38775 | LeuRS-IN-1 | ||
LeuRS-IN-1 is a highly potent and orally active inhibitor of the leucyl-tRNA synthetase enzyme derived from Mycobacterium tuberculosis (M.tb LeuRS). It exhibits significant inhibitory activity against M.tb LeuRS with IC ... |